Lysosomes withhold promising, yet unexplored, functions within B immune cell activation signaling. The positioning of lysosomes and their metabolic status contributes to e.g. cell motility and extracellular enzyme release.

Our research group focuses on understanding the outcome of the molecular heterogeneity in DLBCL B cell lymphoma: nothing is known of lysosome targeting in clinically different DLBCLs subtypes.

Can lysosome functions be modulated in B immune cells to control activation signaling?